SATURDAY
11:00 - 13:00 Registration
13:00 – 13:30 Opening & Welcome
Klaus Cussler (on behalf of the Organising Committee)
Dr. Bernhard Polten, Federal Ministry of Consumer Protection, Food and Agriculture
Prof. Dr. Reiner Wittkowski, Vice President of the BfR
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13:30 – 15:00 Session I: The importance of general and specific clinical signs for determining
humane endpoints.
Chair: Coenraad Hendriksen
Keynote: David Morton (University of Birmingham, UK)
Careful monitoring of animals for the determination of humane endpoints
Presentations: Gilly Griffin (Canadian Council on Animal Care, Canada)
CCAC guidelines on: choosing an appropriate endpoint in experiments using animals
for research, teaching and testing
Kathryn Ryder (Home Office United Kingdom)
Humane endpoints and research in fish
Egbert Hanenberg (Intervet, The Netherlands)
The Use of Humane Endpoints in chickens
15:50 – 16:40 Session II: Humane Endpoints in Cancer Research.
Chair: David Morton
Keynote: Merel Ritskes-Hoitinga (University of Southern Denmark)
Hidden cancers and humane endpoints
Presentations: Jim Wallace (Science Associates, UK)
Application of Humane Endpoints in Cancer Research
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15:20 – 15:50 Coffee break
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16:40 – 18:20 Session III: Application of Humane end points in practice.
Chair: David Morton
Coenraad Hendriksen (NCA and Netherlands Vaccine Institute)
Obstacles in the implementation of humane endpoints
Iris Boumans (Netherlands Centre for Alternatives to Animal Use)
Humane endpoints in biomedical research: an interactive CD ROM
Jann Hau (University of Copenhagen and Rigshospitalet, DK)
Stress - assessed by quantification of non-invasive stress markers
René Remie (Solvay Pharmaceuticals, Belgium)
Radio-Telemetry: A tool in humane endpoint determination?
Derek Fry (Home Office, UK)
Humane Endpoints: Experiences of the UK Home Office Inspectorate
Heidemarie Ratsch (Berlin Office for Occupational Safety, Protection of Health and Technical Safety, Germany)
The Importance of Animal Welfare Officers and the Commission according
to Article 15 of the German Animal Welfare Act regarding Human Endpoints
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~ 18:15 Reception: Drinks & Snacks
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SUNDAY
09:00 – 11:05 Session IV: Toxicology & Pharmacology
Chair: N.N.
Keynote: Hermann Koeter (European Food Safety Authority, Belgium)
Thoughts of hope and reality concerning humane endpoints
Presentations: Bill Stokes (ICCVAM, United States)
Humane Endpoints for Animals Used in Biomedical Research and Testing:
Best Practices,
Policies, and Progress in the U.S.
Pierre Guittin (Sanofi-Aventis, France)
Criteria and decision-making process for anticipating endpoints on preclinical development studies
Raymond Poon (Environmental Health Science Bureau, Canada)
Urinary biomarkers as non-invasive toxicological endpoints - recent advances
Johan Descamps (GlaxoSmithKline-Bio, Belgium)
Humane Endpoints and 3R-principles in the Quality Control of Human Pharmaceuticals and Vaccines
Erwin Falkner (Medical University Vienna and zet, Austria)
In Ovo Models for Tissue Engineering: Proposal to Use an Early Endpoint in the HET-CAM Test
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11:05 – 11:35 Coffee break
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11:35 – 13:15 Session V: Microbiology & Vaccine Testing
Chair: Klaus Cussler
Keynote: Ernest D. Olfert (University of Saskatchewan, Canada)
Animals in Infectious Disease Research – Balancing Welfare, Humane Endpoints and Valid Scientific Outcomes
Presentations: Karl Andrutis (Tufts University, United States)
Impediments to Humane Endpoints in Infectious Disease Research
Nick Reed (VLA, UK)
Refinement of the Canine Leptospirosis Vaccine Potency Test: Experiences and Observations
Lukas Bruckner (IVI, Switzerland)
Application of humane endpoints in veterinary vaccine testing in target species
Yasemin Süzer (PEI, Germany)
Humane endpoints upon in vivo characterization of candidate third generation smallpox vaccine
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~ 13:30 Closing & Farewell
Coenraad Hendriksen (on behalf of the Organising Committee)
~ 13:45 Lunch Buffet at the Cafeteria of the BfR